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The TicoVac® primary dose series is recommended to be completed at least 1 week prior to potential exposure to TBEV.1
A booster dose (fourth dose) may be given at least 3 years after completion of the primary immunization series if ongoing exposure or re-exposure to TBEV is expected.1
Dosing, Schedule and Administration Primary Vaccination Series
The vaccination dose and timing for the 3-dose primary TBE vaccine series vary by age (Box 2).
1–15 years: 3 doses (0.25 mL each) administered intramuscularly (IM) with the first 2 doses administered 1 to 3 months apart and the third dose administered 5 to 12 months after dose 2.
16 years and older: 3 doses (0.5 mL each) administered IM with the first 2 doses administered 14 days to 3 months apart and the third dose administered 5 to 12 months after dose 2.
For all age groups, the 3-dose primary immunization series should be completed at least 1 week before potential exposure to TBE virus.
For persons (e.g., travelers) who cannot complete the 3-dose primary series, see section “Immunologic Response After an Incomplete Primary Series (1 or 2 Doses) in Adults and Children” of the ACIP Recommendations for additional information.
Booster Dose
For all age groups, a booster dose (i.e., fourth dose) can be administered at least 3 years after completion of the primary 3-dose TBE vaccine series if ongoing exposure or re-exposure to TBE virus is expected.
No ACIP recommendations are made on the need for subsequent booster doses.
1–15 years: 0.25 mL dose administered IM at ≥3 years after completion of primary series.
16 years and older: 0.5 mL dose administered IM at ≥3 years after completion of primary series.
There are currently no U.S. recommendations on the need for subsequent booster doses.
Discover more about TBE with these helpful resources. You can access HCP and patient materials via the Resources tab.
To report an adverse event, please call 1-800-438-1985
Pfizer for Professionals 1-800-505-4426
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